Activity of LpxC inhibitors on carbapenemase-producing Citrobacter spp. clinical isolates

ABSTRACT: Objective: Citrobacter spp. are commonly found in the human intestine and can cause antibiotic-resistant infections. Inhibitors of LpxC, an enzyme involved in the synthesis of lipid A, have demonstrated potent activity against multiple Gram-negative species, but their activity in Citrobac...

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Bibliografiske detaljer

Principais autores:	Víctor Vinuesa, Raquel Cruces, Javier E. Cañada-García, Jesús Oteo-Iglesias, Andrés Corral-Lugo, Michael J. McConnell
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2025-09-01
Serier:	Journal of Global Antimicrobial Resistance
Fag:	Citrobacter spp. Antibiotic resistance Carbapenemase LpxC inhibitors Clinical isolates Strain collection
Online adgang:	http://www.sciencedirect.com/science/article/pii/S221371652500178X
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