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CD4+ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent

Abstract CD4+ T cells are necessary to control intracellular bacterial infections, but the role of sex in these infections is poorly understood. Here we show that upon challenge with Salmonella, a model intracellular bacterium, more male mice succumb to infection than females, despite having more Sa...

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Үндсэн зохиолчид: Shaina J. D’Souza, Rebecca M. Horowitz, Louay Bachnak, Victoria E. Immethun, Matthew S. Godwin, Charlotte M. Hankin, Vanessa M. Limbert, David L. Bauer, Alex J. Plaisance, Avery M. Burke, Lisa A. Morici, Hyemin Lee, Hua Lu, Ryan Craig, Jonathan R. Kurtz, Sophia A. Blessinger, Sarah H. Lindsey, Franck Mauvais-Jarvis, Ali Yasrebi, Victoria Appel, Troy A. Roepke, John A. McLachlan, James B. McLachlan
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2026-04-01
Цуврал:Nature Communications
Онлайн хандалт:https://doi.org/10.1038/s41467-026-71805-1
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