CD4+ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent

Abstract CD4+ T cells are necessary to control intracellular bacterial infections, but the role of sex in these infections is poorly understood. Here we show that upon challenge with Salmonella, a model intracellular bacterium, more male mice succumb to infection than females, despite having more Sa...

Full beskrivning

Bibliografiska uppgifter

Huvudupphov:	Shaina J. D’Souza, Rebecca M. Horowitz, Louay Bachnak, Victoria E. Immethun, Matthew S. Godwin, Charlotte M. Hankin, Vanessa M. Limbert, David L. Bauer, Alex J. Plaisance, Avery M. Burke, Lisa A. Morici, Hyemin Lee, Hua Lu, Ryan Craig, Jonathan R. Kurtz, Sophia A. Blessinger, Sarah H. Lindsey, Franck Mauvais-Jarvis, Ali Yasrebi, Victoria Appel, Troy A. Roepke, John A. McLachlan, James B. McLachlan
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Portfolio 2026-04-01
Serie:	Nature Communications
Länkar:	https://doi.org/10.1038/s41467-026-71805-1
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!