A novel validated UPLC method for quantitation of lopinavir and ritonavir in bulk drug and pharmaceutical formulation with its impurities

A simple gradient Ultra Performance liquid chromatographic method (UPLC) was developed for determination of lopinavir and ritonavir from its related impurities and assay for the first time. This method involves the use of a C18 (Acquity UPLC BEH C18, 50 × 2.1 mm, 1.7 µm) column thermostated at 30 oC...

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מידע ביבליוגרפי

Principais autores:	Gnana Deepika Killi, Rama Krishna Maddinapudi, Sathis Kumar Dinakaran, Avasarala Harani
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2014-04-01
סדרה:	Brazilian Journal of Pharmaceutical Sciences
נושאים:	Lopinavir/determinação Ritonavir/determinação Cromatografia Líquida de Ultra Eficiência/análise qualitativa Cromatografia Líquida de Ultra Eficiência/análise quantitativa Fármacos a granel/análise qualitativa Formulações farmacêuticas/análise qualitativa Formulações farmacêuticas/perfil de impureza Fármacos a granel/perfil de impureza
גישה מקוונת:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200301&lng=en&tlng=en
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