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High-Risk HLA-DQ Mismatches Are Associated With Adverse Outcomes After Lung Transplantation

Human leukocyte antigen (HLA) mismatches (MM) between donor and recipient lead to eplet MM (epMM) in lung transplantation (LTX), which can induce the development of de-novo donor-specific HLA-antibodies (dnDSA), particularly HLA-DQ-dnDSA. Aim of our study was to identify risk factors for HLA-DQ-dnDS...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Lisa Kleid, Julia Walter, Patrick Moehnle, Christian Wichmann, Julia Kovács, Andreas Humpe, Christian Schneider, Sebastian Michel, Nikolaus Kneidinger, Michael Irlbeck, Jan Fertmann, Andrea Dick, Teresa Kauke
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2024-09-01
Rangatū:Transplant International
Ngā marau:
eplet matching
de novo donor specific antibody
HLA-DQ antibody
risk-stratification
lung transplantation
Urunga tuihono:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13010/full
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