High-Risk HLA-DQ Mismatches Are Associated With Adverse Outcomes After Lung Transplantation

Human leukocyte antigen (HLA) mismatches (MM) between donor and recipient lead to eplet MM (epMM) in lung transplantation (LTX), which can induce the development of de-novo donor-specific HLA-antibodies (dnDSA), particularly HLA-DQ-dnDSA. Aim of our study was to identify risk factors for HLA-DQ-dnDS...

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Auteurs principaux:	Lisa Kleid, Julia Walter, Patrick Moehnle, Christian Wichmann, Julia Kovács, Andreas Humpe, Christian Schneider, Sebastian Michel, Nikolaus Kneidinger, Michael Irlbeck, Jan Fertmann, Andrea Dick, Teresa Kauke
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-09-01
Collection:	Transplant International
Sujets:	eplet matching de novo donor specific antibody HLA-DQ antibody risk-stratification lung transplantation
Accès en ligne:	https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13010/full
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