A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model

Open fractures are at risk of serious infection and, if infected, require several surgical interventions and courses of systemic antibiotics. We investigated a new injectable formulation that simultaneously hardens in vivo to form a porous scaffold for bone repair and delivers antibiotics at high co...

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Detalhes bibliográficos

Principais autores:	JS McLaren, LJ White, HC Cox, W Ashraf, CV Rahman, GW Blunn, AE Goodship, RA Quirk, KM Shakesheff, R Bayston, BE Scammell
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Forum Multimedia Publishing LLC 2014-06-01
Colecção:	European Cells & Materials
Assuntos:	PLGA biodegradable scaffold infection in vivo bone ingrowth
Acesso em linha:	http://www.ecmjournal.org/journal/papers/vol027/pdf/v027a24.pdf
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