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A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model

Open fractures are at risk of serious infection and, if infected, require several surgical interventions and courses of systemic antibiotics. We investigated a new injectable formulation that simultaneously hardens in vivo to form a porous scaffold for bone repair and delivers antibiotics at high co...

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Wedi'i Gadw mewn:
Prif Awduron: JS McLaren, LJ White, HC Cox, W Ashraf, CV Rahman, GW Blunn, AE Goodship, RA Quirk, KM Shakesheff, R Bayston, BE Scammell
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Forum Multimedia Publishing LLC 2014-06-01
Cyfres:European Cells & Materials
Pynciau:
PLGA
biodegradable scaffold
infection
in vivo
bone ingrowth
Mynediad Ar-lein:http://www.ecmjournal.org/journal/papers/vol027/pdf/v027a24.pdf
Tagiau: Ychwanegu Tag
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