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Feedback regulation of mitochondrial homeostasis via Wnt/β-catenin signaling

Cellular abundance of mitochondria is dynamically regulated. We could recently show that dysfunctional mitochondria release the phosphatase PGAM family member 5 (PGAM5) into the cytosol, where it interacts with the Wnt signaling-component AXIN1 and dephosphorylates AXIN1-bound β-catenin (CTNNB1) the...

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Detalles Bibliográficos
Principais autores: Dominic B. Bernkopf, Jürgen Behrens
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2018-05-01
Series:Molecular & Cellular Oncology
Assuntos:
Acceso en liña:http://dx.doi.org/10.1080/23723556.2018.1458015
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