PIKfyve regulates melanosome biogenesis.
PIKfyve, VAC14, and FIG4 form a complex that catalyzes the production of PI(3,5)P2, a signaling lipid implicated in process ranging from lysosome maturation to neurodegeneration. While previous studies have identified VAC14 and FIG4 mutations that lead to both neurodegeneration and coat color defect...
Gorde:
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science (PLoS)
2018-03-01
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| Saila: | PLoS Genetics |
| Sarrera elektronikoa: | https://escholarship.org/uc/item/3rg2c4qs |
| Etiketak: |
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