Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo

Exogenous amyloid beta peptides cause distinct transcriptomic responses in microglia cultures that are not fully replicated in an amyloid mouse model or identified microglial subpopulations in vivo. Aggregation and accumulation of amyloid-β (Aβ) is a defining feature of Alzheimer’s disease pathology...

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Autors principals:	Karen N McFarland, Carolina Ceballos, Awilda Rosario, Thomas Ladd, Brenda Moore, Griffin Golde, Xue Wang, Mariet Allen, Nilüfer Ertekin-Taner, Cory C Funk, Max Robinson, Priyanka Baloni, Noa Rappaport, Paramita Chakrabarty, Todd E Golde
Format:	Artigo
Idioma:	Inglês
Publicat:	Life Science Alliance LLC 2021-07-01
Col·lecció:	Life Science Alliance
Accés en línia:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101108
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