Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo

Exogenous amyloid beta peptides cause distinct transcriptomic responses in microglia cultures that are not fully replicated in an amyloid mouse model or identified microglial subpopulations in vivo. Aggregation and accumulation of amyloid-β (Aβ) is a defining feature of Alzheimer’s disease pathology...

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Autores principales:	Karen N McFarland, Carolina Ceballos, Awilda Rosario, Thomas Ladd, Brenda Moore, Griffin Golde, Xue Wang, Mariet Allen, Nilüfer Ertekin-Taner, Cory C Funk, Max Robinson, Priyanka Baloni, Noa Rappaport, Paramita Chakrabarty, Todd E Golde
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Life Science Alliance LLC 2021-07-01
Colección:	Life Science Alliance
Acceso en línea:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101108
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