Structural properties of the HNF-1A transactivation domain
Hepatocyte nuclear factor 1α (HNF-1A) is a transcription factor with important gene regulatory roles in pancreatic β-cells. HNF1A gene variants are associated with a monogenic form of diabetes (HNF1A-MODY) or an increased risk for type 2 diabetes. While several pancreatic target genes of HNF-1A have...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2023-10-01
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| Serier: | Frontiers in Molecular Biosciences |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fmolb.2023.1249939/full |
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