Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid.

Caspase-8 is involved in death receptor-mediated apoptosis in type II cells, the proapoptotic programme of which is triggered by truncated Bid. Indeed, caspase-8 and Bid are the known intermediates of this signalling pathway. Cardiolipin has been shown to provide an anchor and an essential activatin...

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Principais autores:	Olivier Jalmar, Liberty François-Moutal, Ana-Jesus García-Sáez, Mark Perry, Thierry Granjon, François Gonzalvez, Eyal Gottlieb, Jesus Ayala-Sanmartin, Beate Klösgen, Petra Schwille, Patrice X Petit
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2013-01-01
叢編:	PLoS ONE
在線閱讀:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23418437/?tool=EBI
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