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High-throughput full-length single-cell mRNA-seq of rare cells.

Single-cell characterization techniques, such as mRNA-seq, have been applied to a diverse range of applications in cancer biology, yielding great insight into mechanisms leading to therapy resistance and tumor clonality. While single-cell techniques can yield a wealth of information, a common bottle...

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Autors principals: Chin Chun Ooi, Gary L Mantalas, Winston Koh, Norma F Neff, Teruaki Fuchigami, Dawson J Wong, Robert J Wilson, Seung-Min Park, Sanjiv S Gambhir, Stephen R Quake, Shan X Wang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2017-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC5706670?pdf=render
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