C-di-AMP sensitizes colorectal cancer to CD47 antibodies by activating NF-κB to promote macrophage phagocytosis
Abstract Objective Developing effective therapeutic strategies for colorectal cancer (CRC) presents a significant clinical challenge. Although immune checkpoint blockade therapies, such as the CD47 blockade, have shown promise, their efficacy is often limited by suboptimal responses and associated t...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2026-01-01
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| coleção: | Cell Communication and Signaling |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12964-026-02703-8 |
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