Epac2 Deficiency Compromises Adaptation to Dietary Acidification by Decreasing H+ Transport in the Renal Nephron
Abstract Kidneys are central in maintaining acid-base homeostasis by recovering filtered bicarbonate (HCO3−) in the proximal tubule and by secreting H+ in the collecting duct. Here, we demonstrate a critical role of the exchange protein directly activated by cAMP (Epac) signaling, and particularly t...
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| المؤلفون الرئيسيون: | , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Physiological Society
2025-01-01
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| سلاسل: | Function |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://journals.physiology.org/doi/10.1093/function/zqaf048 |
| الوسوم: |
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