Early glycolytic reprogramming controls microglial inflammatory activation

Abstract Background Microglial activation-mediated neuroinflammation plays an important role in the progression of neurodegenerative diseases. Inflammatory activation of microglial cells is often accompanied by a metabolic switch from oxidative phosphorylation to aerobic glycolysis. However, the rol...

Descrición completa

Detalles Bibliográficos

Principais autores:	Junjie Cheng, Rong Zhang, Zhirou Xu, Youliang Ke, Renjuan Sun, Huicui Yang, Xiaohu Zhang, Xuechu Zhen, Long-Tai Zheng
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2021-06-01
Series:	Journal of Neuroinflammation
Assuntos:	Glycolytic inhibitors Microglial cells Neuroinflammation NF-κB 2-DG
Acceso en liña:	https://doi.org/10.1186/s12974-021-02187-y
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!