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Glycolytic Reprogramming in Lung Adenocarcinoma:
Molecular Mechanisms, Metabolic Biomarkers and Targeted Therapeutic Strategies

Lung adenocarcinoma (LUAD) is the most common and highly aggressive subtype of non-small cell lung cancer, characterized by metabolic reprogramming with enhanced glycolysis. Upregulation of key glycolytic enzymes [hexokinase 2 (HK2), pyruvate kinase M2 (PKM2), lactate dehydrogenase A (LDHA)] and lac...

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Hlavní autoři: Caini ZHANG, Yu FU, Huiqin FENG, Yuqing PAN, Ya LI, Chenglu HE
Médium: Artigo
Jazyk:Chinês
Vydáno: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2026-04-01
Edice:Chinese Journal of Lung Cancer
Témata:
On-line přístup:http://dx.doi.org/10.3779/j.issn.1009-3419.2026.102.07
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