Strategies to circumvent the CFTR defect in cystic fibrosis

Geahča maid

• The F508del-CFTR trafficking correctors elexacaftor and tezacaftor are CFTR-independent Ca2+-mobilizing agonists normalizing abnormal Ca2+ levels in human airway epithelial cells
  Dahkki: Manuella Lévêque, et al.
  Almmustuhtton: (2024-12-01)
• Strategies to circumvent the CFTR defect in cystic fibrosis
  Dahkki: Frederic eBecq, et al.
  Almmustuhtton: (2013-08-01)
• Ouabain mimics low temperature rescue of F508del-CFTR in cystic fibrosis epithelial cells
  Dahkki: Donglei eZhang, et al.
  Almmustuhtton: (2012-10-01)
• Beyond the mutations: spatiotemporal regulation of CFTR by cAMP and calcium signaling in epithelial physiology and cystic fibrosis
  Dahkki: Arpad Varga, et al.
  Almmustuhtton: (2025-12-01)
• Regulatory crosstalk by protein kinases on CFTR trafficking and activity
  Dahkki: Carlos Miguel eFarinha, et al.
  Almmustuhtton: (2016-01-01)