LncMAPK6 drives MAPK6 expression and liver TIC self-renewal

Abstract Background Liver tumor initiating cells (TICs) have self-renewal and differentiate capacities, and largely contribute to tumor initiation, metastasis and drug resistance. MAPK signaling is a critical pathway in many biological processes, while its role in liver TICs hasn’t been explored. Me...

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Autors principals:	Guanqun Huang, Hui Jiang, Yueming He, Ye Lin, Wuzheng Xia, Yuanwei Luo, Min Liang, Boyun Shi, Xinke Zhou, Zhixiang Jian
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-05-01
Col·lecció:	Journal of Experimental & Clinical Cancer Research
Matèries:	MAPK6 lncMAPK6 Liver TIC Self-renewal Tumor targeting
Accés en línia:	http://link.springer.com/article/10.1186/s13046-018-0770-y
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