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ERN1 dependent impact of glutamine and glucose deprivations on the pyruvate dehydrogenase genes expression in glioma cells

Objective. The aim of the present study was to investigate the expression of pyruvate dehydrogenase genes such as PDHA1, PDHB, DLAT, DLD, and PDHX in U87 glioma cells in response to glutamine and glucose deprivations in control glioma cells and endoplasmic reticulum to nucleus signaling 1 (ERN1) kno...

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Principais autores: Shatokhina Hanna O., Khita Olena O., Minchenko Dmytro O., Tsymbal Dariia O., Luzina Olha R., Danilovskyi Serhiy V., Sliusar Myroslava Y., Levadna Liudmyla O., Minchenko Oleksandr H.
Format: Artigo
Sprog:Inglês
Udgivet: Sciendo 2022-10-01
Serier:Endocrine Regulations
Fag:
u87 glioma cells
ern1 knockdown
glutamine and glucose deprivations
pyruvate dehydrogenase
gene expression
Online adgang:https://doi.org/10.2478/enr-2022-0027
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