Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells

Objective. Glucose and glutamine supply as well as serine synthesis and endoplasmic reticulum (ER) stress are important factors of glioblastoma growth. Previous studies showed that the knockdown of ERN1 (ER to nucleus signaling 1) suppressed glioblastoma cell proliferation and modified the sensitivi...

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Principais autores:	Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Minchenko Dmytro O., Viletska Yuliia M., Halkin Oleh V., Levadna Liudmyla O., Cherednychenko Anastasiia A., Khikhlo Yevgen P.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Sciendo 2024-01-01
סדרה:	Endocrine Regulations
נושאים:	ern1 knockdown glucose deprivation glutamine deprivation psat1 psph atf4 gene expression u87mg glioblastoma cells
גישה מקוונת:	https://doi.org/10.2478/enr-2024-0010
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!