Cathepsin K Expression in Castration-Resistant Prostate Carcinoma: A Therapeutical Target for Patients at Risk for Bone Metastases

Background The lysosomal cysteine protease cathepsin K is involved in bone remodeling and is also expressed in the peritumoral stroma of carcinomas arising from different organs. A new generation of cathepsin K inhibitors blocking the RANKL/RANK pathway are being developed. We sought to investigate...

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Bibliografische gegevens

Hoofdauteurs:	Enrico Munari, Luca Cima, Francesco Massari, Francesco Bertoldo, Antonio Benito Porcaro, Anna Caliò, Giulio Riva, Elisa Ciocchetta, Chiara Ciccarese, Alessandra Modena, Roberto Iacovelli, Teodoro Sava, Albino Eccher, Claudio Ghimenton, Giampaolo Tortora, Walter Artibani, Giovanni Novella, Giuseppe Bogina, Giuseppe Zamboni, Francesca Sanguedolce, Alessandro D'Amuri, Guido Martignoni, Matteo Brunelli
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	SAGE Publishing 2017-04-01
Reeks:	The International Journal of Biological Markers
Online toegang:	https://doi.org/10.5301/jbm.5000246
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