Cathepsin K Expression in Castration-Resistant Prostate Carcinoma: A Therapeutical Target for Patients at Risk for Bone Metastases

Background The lysosomal cysteine protease cathepsin K is involved in bone remodeling and is also expressed in the peritumoral stroma of carcinomas arising from different organs. A new generation of cathepsin K inhibitors blocking the RANKL/RANK pathway are being developed. We sought to investigate...

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Автори:	Enrico Munari, Luca Cima, Francesco Massari, Francesco Bertoldo, Antonio Benito Porcaro, Anna Caliò, Giulio Riva, Elisa Ciocchetta, Chiara Ciccarese, Alessandra Modena, Roberto Iacovelli, Teodoro Sava, Albino Eccher, Claudio Ghimenton, Giampaolo Tortora, Walter Artibani, Giovanni Novella, Giuseppe Bogina, Giuseppe Zamboni, Francesca Sanguedolce, Alessandro D'Amuri, Guido Martignoni, Matteo Brunelli
Формат:	Artigo
Мова:	Inglês
Опубліковано:	SAGE Publishing 2017-04-01
Серія:	The International Journal of Biological Markers
Онлайн доступ:	https://doi.org/10.5301/jbm.5000246
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Cathepsin K Expression in Castration-Resistant Prostate Carcinoma: A Therapeutical Target for Patients at Risk for Bone Metastases

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