Generation of human induced pluripotent stem cell (hiPSC) lines from patients with extreme high and low polygenic scores for QT interval

Long QT syndrome (LQTS), an inherited cardiac arrhythmia syndrome with congenital and drug-induced presentations and known monogenic and polygenic contributions, represents a significant clinical challenge due to its complex genetic underpinning and propensity for fatal arrhythmias. In this study, w...

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書誌詳細

主要な著者:	Devyn Mitchell, Rizwan Ullah, Loren Vanags, Alex Shen, Luke Jones, William Morris, Matthew J. O’Neill, Giovanni Davogustto, Christian Shaffer, Dan Roden, Ben Shoemaker, Hollie Williams, Teresa Strickland, Taylor Agee, Christopher Johnson, Brett Kroncke
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2025-04-01
シリーズ:	Stem Cell Research
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S1873506125000418
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