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Enhanced cytotoxicity of natural killer cells following the acquisition of chimeric antigen receptors through trogocytosis.

Natural killer (NK) cells have the capacity to target tumors and are ideal candidates for immunotherapy. Viral vectors have been used to genetically modify in vitro expanded NK cells to express chimeric antigen receptors (CARs), which confer cytotoxicity against tumors. However, use of viral transdu...

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書誌詳細
主要な著者: Fu-Nan Cho, Tsung-Hsien Chang, Chih-Wen Shu, Ming-Chin Ko, Shuen-Kuei Liao, Kang-Hsi Wu, Ming-Sun Yu, Shyh-Jer Lin, Ying-Chung Hong, Chien-Hsun Chen, Chien-Hui Hung, Yu-Hsiang Chang
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2014-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4196898?pdf=render
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