Structural insights into the mechanism of phosphate recognition and transport by XPR1

Abstract XPR1 is the sole protein known to transport inorganic phosphate (Pi) out of cells, a function conserved across species from yeast to mammals. Human XPR1 variants lead to cerebral calcium-phosphate deposition and primary familial brain calcification (PFBC), a hereditary neurodegenerative dis...

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Detalhes bibliográficos

Principais autores:	Wenhui Zhang, Yanke Chen, Zeyuan Guan, Yong Wang, Meng Tang, Zhangmeng Du, Jie Zhang, Meng Cheng, Jiaqi Zuo, Yan Liu, Qiang Wang, Yanjun Liu, Delin Zhang, Ping Yin, Ling Ma, Zhu Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-01-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-55471-9
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