Structural insights into the mechanism of phosphate recognition and transport by XPR1
Abstract XPR1 is the sole protein known to transport inorganic phosphate (Pi) out of cells, a function conserved across species from yeast to mammals. Human XPR1 variants lead to cerebral calcium-phosphate deposition and primary familial brain calcification (PFBC), a hereditary neurodegenerative dis...
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| Hlavní autoři: | , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2025-01-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-024-55471-9 |
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