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Physicochemical properties and cytochromes P-450 kinetics of a trifluoroacetamido derivative of acetaminophen

Acetaminophen (N-acetyl-para-aminophenol, APAP) is a commonly used analgesic and antipyretic drug. While acetaminophen is generally safe when taken at therapeutic doses, it causes severe liver and kidney damage at overdose quantities. Cytochromes P-450 (CYP) catalyze the transformation of APAP to N-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joshua A. Boldon, Thomas A. Shell
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2023-12-01
Cyfres:Results in Chemistry
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2211715623003685
Tagiau: Ychwanegu Tag
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