Physicochemical properties and cytochromes P-450 kinetics of a trifluoroacetamido derivative of acetaminophen
Acetaminophen (N-acetyl-para-aminophenol, APAP) is a commonly used analgesic and antipyretic drug. While acetaminophen is generally safe when taken at therapeutic doses, it causes severe liver and kidney damage at overdose quantities. Cytochromes P-450 (CYP) catalyze the transformation of APAP to N-...
שמור ב:
| Principais autores: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2023-12-01
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| סדרה: | Results in Chemistry |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2211715623003685 |
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