Multiscale simulations reveal the role of PcrA helicase in protecting against spontaneous point mutations in DNA
Abstract Proton transfer across hydrogen bonds in DNA can produce non-canonical nucleobase dimers and is a possible source of single-point mutations when these forms mismatch under replication. Previous computational studies have revealed this process to be energetically feasible for the guanine-cyt...
Uloženo v:
| Hlavní autoři: | , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2023-12-01
|
| Edice: | Scientific Reports |
| On-line přístup: | https://doi.org/10.1038/s41598-023-48119-z |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|