Mutagenic Effects Induced by the Attack of NO2 Radical to the Guanine-Cytosine Base Pair

We investigate the attack of the nitrogen dioxide radical (NO2) to the guanine-cytosine (GC) base pair and the subsequent tautomeric reactions able to induce mutations, by means of density functional theory (DFT) calculations. The conducted simulations allow us to identify the most reactive sites of...

Cur síos iomlán

Sábháilte in:

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	José Pedro eCerón-Carrasco, Alberto eRequena, José eZúñiga, Denis eJacquemin
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2015-03-01
Sraith:	Frontiers in Chemistry
Ábhair:	Density Functional Theory Computational Chemistry Induced mutation Tautomeric equilibria Proton transfer reaction Rare tautomers
Rochtain ar líne:	http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00013/full
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!

Mutagenic Effects Induced by the Attack of NO2 Radical to the Guanine-Cytosine Base Pair

Míreanna comhchosúla