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Arcyriaflavin A, a cyclin D1/CDK4 inhibitor, suppresses tumor growth, migration, and invasion of metastatic melanoma cells

Abstract Background Despite advancements in targeted therapy and immunotherapy, cutaneous melanoma continues to have a high mortality rate and poor prognosis, with therapies having limited efficacy in advanced melanoma. Therefore, it is crucial to develop novel therapeutics with proven clinical pote...

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Principais autores: Dokyeong Kim, Junseong Park, Yoon-Seob Kim, Okcho Na, Minyoung Park, Songzi Zhang, Sumin Cho, Yeun-Jun Chung
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2025-02-01
סדרה:Cancer Cell International
נושאים:
גישה מקוונת:https://doi.org/10.1186/s12935-025-03675-4
תגים: הוספת תג
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