Genetic Investigation of Corrected QT Interval Sensitivity to Oral Bepridil Hydrochloride Hydrate in Patients With Atrial Fibrillation

Background Bepridil is an antiarrhythmic drug used to treat paroxysmal atrial fibrillation; however, its use is limited by corrected QT interval (QTc) prolongation and the risk of ventricular arrhythmias. This study aimed to identify genetic variants associated with bepridil‐associated QTc prolongat...

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Huvudupphov:	Naoki Ishibashi, Motoki Furutani, Mika Nakashima, Shunsuke Ishida, Junji Maeda, Takumi Sakai, Naoto Oguri, Shogo Miyamoto, Shunsuke Miyauchi, Sho Okamura, Yousaku Okubo, Takehito Tokuyama, Noboru Oda, Takumi Nishiki, Risa Mitsumori, Shumpei Niida, Kouichi Ozaki, Daichi Shigemizu, Hideki Itoh, Yukiko Nakano
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2026-06-01
Serie:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Ämnen:	bepridil genome‐wide association study QTc prolongation
Länkar:	https://www.ahajournals.org/doi/10.1161/JAHA.125.047046
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