Hereditary breast and ovarian cancer syndrome (BRCA) gene: Concept, pathways, therapeutics, and future
Hereditary breast and ovarian cancers are most commonly caused by mutations in BRCA1 and 2 genes. These are autosomal dominant mutations with high penetrance into subsequent generations. Affected individuals have deficiency in DNA repair mechanisms such as double strand DNA breaks (DSB) and non-homo...
Збережено в:
| Автори: | , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-01-01
|
| Серія: | Indian Journal of Medical and Paediatric Oncology |
| Предмети: | |
| Онлайн доступ: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=9;epage=14;aulast=Tamhankar |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|