Sequence dependencies and mutation rates of localized mutational processes in cancer
Abstract Background Cancer mutations accumulate through replication errors and DNA damage coupled with incomplete repair. Individual mutational processes often show nucleotide sequence and functional region preferences. As a result, some sequence contexts mutate at much higher rates than others, wit...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2023-08-01
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| coleção: | Genome Medicine |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13073-023-01217-z |
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