miRNA activity inferred from single cell mRNA expression
Abstract High throughput single-cell RNA sequencing (scRNAseq) can provide mRNA expression profiles for thousands of cells. However, miRNAs cannot currently be studied at the same scale. By exploiting that miRNAs bind well-defined sequence motifs and typically down-regulate target genes, we show tha...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2021-04-01
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| Serie: | Scientific Reports |
| Accesso online: | https://doi.org/10.1038/s41598-021-88480-5 |
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