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Irx1 mechanisms for oral epithelial basal stem cell plasticity during reepithelialization after injury

The oral mucosa undergoes daily insults, and stem cells in the epithelial basal cell layer regenerate gingiva tissue to maintain oral health. The Iroquois Homeobox 1 (IRX1) protein is expressed in the stem cell niches in human/mouse oral epithelium and mesenchyme under homeostasis. We found that Irx...

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Detalhes bibliográficos
Main Authors: Dan Su, Tadkamol Krongbaramee, Samuel Swearson, Yan Sweat, Mason Sweat, Fan Shao, Steven Eliason, Brad A. Amendt
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2025-01-01
Colecção:JCI Insight
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Acesso em linha:https://doi.org/10.1172/jci.insight.179815
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