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PBLD promotes IRF3 mediated the type I interferon (IFN-I) response and apoptosis to inhibit viral replication

Abstract Recent studies have implicated the phenazine biosynthesis-like domain-containing protein (PBLD) in the negative regulation of the development and progression of various cancers. However, its function in viral infection remains unknown. In this study, we found that PBLD plays important roles...

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Autors principals: Hongchao Zhu, Peili Hou, Fengyun Chu, Xingyu Li, Wenjia Zhang, Xiaonan Sun, Yu Liu, Guimin Zhao, Yuwei Gao, Daniel Chang He, Hongmei Wang, Hongbin He
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2024-10-01
Col·lecció:Cell Death and Disease
Accés en línia:https://doi.org/10.1038/s41419-024-07083-w
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