KAT2B inhibits proliferation and invasion via inactivating TGF-β/Smad3 pathway-medicated autophagy and EMT in epithelial ovarian cancer

Abstract Lysine acetyltransferase 2B (KAT2B) plays a crucial role in epigenetic regulation and tumor pathogenesis. Our study investigates KAT2B’s function in epithelial ovarian cancer (EOC) using in vivo and in vitro methods. Immunohistochemistry showed the KAT2B expression in EOC tissues. RNA seque...

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Bibliografische Detailangaben

Hauptverfasser:	Yuqin Yao, Yuna Niu, Honggui Zhou, Min Yong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-01-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Epithelial ovarian cancer KAT2B Autophagy SMAD7 EMT
Online-Zugang:	https://doi.org/10.1038/s41598-024-83977-1
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