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KAT2B inhibits proliferation and invasion via inactivating TGF-β/Smad3 pathway-medicated autophagy and EMT in epithelial ovarian cancer

Abstract Lysine acetyltransferase 2B (KAT2B) plays a crucial role in epigenetic regulation and tumor pathogenesis. Our study investigates KAT2B’s function in epithelial ovarian cancer (EOC) using in vivo and in vitro methods. Immunohistochemistry showed the KAT2B expression in EOC tissues. RNA seque...

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Principais autores: Yuqin Yao, Yuna Niu, Honggui Zhou, Min Yong
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2025-01-01
Serija:Scientific Reports
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Online dostop:https://doi.org/10.1038/s41598-024-83977-1
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