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Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

Pathogenic microbes confront an evolutionary conflict between the pressure to maintain genome stability and the need to adapt to mounting external stresses. Bacteria often respond with elevated mutation rates, but little evidence exists of stable eukaryotic hypermutators in nature. Whole genome rese...

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書目詳細資料
Principais autores: R Blake Billmyre, Shelly Applen Clancey, Joseph Heitman
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications Ltd 2017-09-01
叢編:eLife
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在線閱讀:https://elifesciences.org/articles/28802
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