African ST173 Cryptococcus deuterogattii strains are commonly less susceptible to fluconazole: An unclear mechanism of resistance

Objectives: Fluconazole (FCZ), either alone or in combination, is often administered for treatment of cryptococcal meningitis, especially in sub-Saharan Africa. Its extensive use has led to the emergence of FCZ-resistant strains. The mechanisms underlying FCZ resistance are poorly documented for yea...

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Bibliografski detalji

Glavni autori:	S. Bertout, F. Roger, P. Drakulovski, A.S. Martin, T. Gouveia, F. Kassi, H. Menan, D. Krasteva, E. Delaporte, V. Bellet
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2020-06-01
Serija:	Journal of Global Antimicrobial Resistance
Teme:	Cryptococcus gattii species complex Cryptococcus deuterogattii VGII genotype Fluconazole Resistance mechanism
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2213716519302711
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