Bioinformatics-driven identification of pathogenic missense nsSNPs in the human proto-oncogene SRC and cancer susceptibility

SRC is a proto-oncogene that regulates cell proliferation and survival, and its dysregulation is commonly observed in diverse cancers. While SRC kinase dysregulation is well-established as a cancer driver, the functional consequences of its genetic variants, particularly non-synonymous single-nucleo...

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Autores principales:	Md. Shakil Ahamed, Roksana Khanam, K.M. Tanjida Islam, Fahmida Tabassum, Md. Al Amin, Jannatul Fardous, Nadira Hoque Tashpie, A.K.M. Mohiuddin, Shahin Mahmud
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2025-12-01
Colección:	Journal of Genetic Engineering and Biotechnology
Materias:	Proto-oncogene SRC nsSNPs In silico analysis Molecular docking Molecular dynamics simulations
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S1687157X25001623
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