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Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration

Abstract Background AMD is a multifactorial progressive disease of the central retina that leads to severe vision loss among the elderly. Genome-wide association studies in AMD patients and preclinical data have identified a dysregulated complement system and aberrant microglia responses in the path...

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Autors principals: Mandy Hector, Verena Behnke, Paulina Dabrowska-Schlepp, Andreas Busch, Andreas Schaaf, Thomas Langmann, Anne Wolf
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-04-01
Col·lecció:Journal of Neuroinflammation
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Accés en línia:https://doi.org/10.1186/s12974-025-03418-2
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