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Simultaneous prediction of antibody backbone and side-chain conformations with deep learning.

Antibody engineering is becoming increasingly popular in medicine for the development of diagnostics and immunotherapies. Antibody function relies largely on the recognition and binding of antigenic epitopes via the loops in the complementarity determining regions. Hence, accurate high-resolution mo...

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Detalles Bibliográficos
Principais autores: Deniz Akpinaroglu, Jeffrey A Ruffolo, Sai Pooja Mahajan, Jeffrey J Gray
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Acceso en liña:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0258173&type=printable
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