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Simultaneous prediction of antibody backbone and side-chain conformations with deep learning.

Antibody engineering is becoming increasingly popular in medicine for the development of diagnostics and immunotherapies. Antibody function relies largely on the recognition and binding of antigenic epitopes via the loops in the complementarity determining regions. Hence, accurate high-resolution mo...

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Váldodahkkit: Deniz Akpinaroglu, Jeffrey A Ruffolo, Sai Pooja Mahajan, Jeffrey J Gray
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2022-01-01
Ráidu:PLoS ONE
Liŋkkat:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0258173&type=printable
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