Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma

Summary: Extracellular vesicles (EVs) are lipid-based nanosized particles that convey biological material from donor to recipient cells. EVs play key roles in glioblastoma progression because glioblastoma stem-like cells (GSCs) release pro-oncogenic, pro-angiogenic, and pro-inflammatory EVs. However...

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Detalhes bibliográficos

Principais autores:	Gwennan André-Grégoire, Clément Maghe, Tiphaine Douanne, Sara Rosińska, Fiorella Spinelli, An Thys, Kilian Trillet, Kathryn A. Jacobs, Cyndie Ballu, Aurélien Dupont, Anne-Marie Lyne, Florence M.G. Cavalli, Ignacio Busnelli, Vincent Hyenne, Jacky G. Goetz, Nicolas Bidère, Julie Gavard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-10-01
coleção:	iScience
Assuntos:	Cell biology Functional aspects of cell biology Cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004222013906
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