The paracaspase MALT1 controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping

Summary: Glioblastoma stem-like cells (GSCs) compose a tumor-initiating and -propagating population remarkably vulnerable to variation in the stability and integrity of the lysosomal compartment. Previous work has shown that the expression and activity of the paracaspase MALT1 control GSC viability...

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Principais autores:	Clément Maghe, Kilian Trillet, Gwennan André-Grégoire, Mathilde Kerhervé, Laura Merlet, Kathryn A. Jacobs, Kristine Schauer, Nicolas Bidère, Julie Gavard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Cell Reports
Assuntos:	CP: Cancer CP: Cell biology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S221112472301642X
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